Screw vacuum pump in production of vitamin B12 of application
Because of the improvement of the production technology of vitamin B12, the new technology of German screw vacuum pump was adopted. With the development of the pharmaceutical industry, competition is increasingly fierce, the quality of products and production costs determine the survival of enterprises. In the manufacturing process of drugs and intermediates, the requirements for clean vacuum environment are increasingly high, and the cost control is increasingly strict, to ensure that there is an energy-saving and environmentally friendly production process. In addition, taking vitamin B12 has a certain effect on people’s health, so it is very important to ensure the production of vitamin B12 without pollution. This paper mainly analyzes the advantages of screw vacuum pump in the actual application of vitamin B12 production process.
Vitamin B12 calls cobalt amine element again, vitamin B12 in nature is microbial synthesis, higher plant and animal cannot make vitamin B12. Vitamin B12 is the only vitamin that needs the help of an intestinal secretion (endogenous factor) to be absorbed. Some people because intestines and stomach is abnormal, lack this kind of endogenous factor, although the source in dietary is sufficient also can suffer from pernicious anaemia. Vitamin B12 is virtually absent from plant-based foods. It stays in the gut for a long time, taking about three hours (most water-soluble vitamins only take a few seconds) to be absorbed. The main physiological function of vitamin B12 is to participate in the production of bone marrow red blood cells to prevent pernicious anemia; To prevent nerve damage in the brain.
The application value of dry screw vacuum pump in the drying process of vitamin B12 crystal is as follows:
Vitamin B12 has metal cobalt ion and multiple amide groups in its molecular structure, its crystal is in the shape of rod or needle, and its hygroscopicity is strong. Therefore, it must be dried with vacuum and high temperature so that its moisture can meet the customer’s requirements. The equilibrium vacuum degree of traditional water ring vacuum pump in the drying process can only reach 0.09 vacuum degree, and the drying time of most batches of products is more than 7 hours, which not only consumes a lot of energy, but also degrades due to long-term heat in the drying process, which brings huge quality loss to manufacturers. We take advantage of the characteristics of high vacuum degree and large air volume of dry screw vacuum pump, and apply this vacuum pump in the drying process of vitamin B12 products for vacuum drying. It can reach the vacuum degree of 0.098, which can shorten the drying time from more than 8 hours to about 3 hours. After drying, the product quality basically has no degradation, which greatly reduces the damage of high temperature to vitamin B12.
To sum up, the screw vacuum pump is very successful in practical application in the production process of vitamin B12. It not only improves the recovery of ketone in concentration process by nearly 30%, but also avoids the influence of drying process on product quality. The equipment can bring huge economic benefits for the production of similar products.
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